SCHEMBL28567776

SCHEMBL28567776

[c]1cccc2c(-c3ccncc3)csc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.38
SMN1; SMN2 Q16637 5/20 0.38
MAPT P10636 3/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
KDM4E B2RXH2 5/20 0.38
IMPDH2 P12268 2/20 0.38
NPC1 O15118 2/20 0.38
AR P10275 2/20 0.38
CYP17A1 P05093 1/20 0.38
CYP1A2 P05177 1/20 0.38
MAPK1 P28482 1/20 0.38
HSD17B10 Q99714 1/20 0.38
GFER P55789 1/20 0.38
CYP19A1 P11511 2/20 0.37
CDK5 Q00535 4/20 0.34
CDK5R1 Q15078 4/20 0.34
LMNA P02545 3/20 0.33
PIK3CD O00329 1/20 0.33
NOTUM Q6P988 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21295628 0.86 CYP17A1 (0.36) RAB9ASMN1; SMN2MAPTKMT2AMEN1
SCHEMBL28570251 0.84 CYP19A1 (0.46) RAB9AMAPTKDM4ENPC1CYP1A2
SCHEMBL21295909 0.76 MAPK14 (0.39) RAB9ASMN1; SMN2MAPTKMT2AKDM4E
SCHEMBL28570834 0.76 CYP19A1 (0.44) RAB9ASMN1; SMN2MAPTKMT2AMEN1
SCHEMBL21295804 0.72 RAB9A (0.38) RAB9ASMN1; SMN2MAPTKMT2AMEN1
SCHEMBL547079 0.71 ERN1 (0.32)
SCHEMBL21295936 0.71 CYP2A6 (0.47) RAB9ASMN1; SMN2MAPTKDM4EIMPDH2
SCHEMBL28745669 0.70 PIK3CD (0.45) RAB9ASMN1; SMN2MAPTKDM4EIMPDH2
SCHEMBL8028211 0.68 CYP2A6 (0.33) CYP1A2
SCHEMBL21297634 0.68 GSK3B (0.37) RAB9ASMN1; SMN2MAPTKDM4EIMPDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed