Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.47 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.38 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.38 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 2/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Azelaic Acid SCHEMBL29191883 | 0.88 | TSHR (0.55) | ALDH1A1TSHRLMNAEPHX2EPHX1 | |
| Cyclohexanol SCHEMBL5495447 | 0.84 | FFAR3 (0.53) | ALDH1A1TSHRLMNAEPHX2EPHX1 | |
| Cyclopentanol SCHEMBL29204411 | 0.84 | FFAR3 (0.53) | ALDH1A1TSHRLMNAEPHX2EPHX1 | |
| Cyclohexanol SCHEMBL241715 | 0.83 | TSHR (0.67) | ALDH1A1TSHREPHX2EPHX1CES2 | |
| Cyclohexanol SCHEMBL30598077 | 0.83 | TSHR (0.67) | ALDH1A1TSHREPHX2EPHX1CES2 | |
| Hexanoate SCHEMBL3271151 | 0.81 | AKR1B1 (0.61) | ALDH1A1TSHROR51E2SLC22A6FFAR1 | |
| Cyclohexanol SCHEMBL9692875 | 0.80 | TSHR (0.62) | ALDH1A1TSHREPHX2EPHX1CES2 | |
| Cyclopentanol SCHEMBL11102072 | 0.80 | TSHR (0.71) | ALDH1A1TSHRLMNAEPHX2EPHX1 | |
| Succinic Acid SCHEMBL27494088 | 0.80 | LMNA (0.75) | ALDH1A1TSHRLMNAEGLN1ALKBH5 | |
| Succinic Acid SCHEMBL27617119 | 0.80 | LMNA (0.75) | ALDH1A1TSHRLMNAEGLN1ALKBH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114032340-B | Novel coronavirus nucleic acid detection kit | 杭州安誉科技有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114032340-A | Novel coronavirus nucleic acid detection kit | 杭州安誉科技有限公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-112921125-A | Novel coronavirus nucleic acid detection kit | 杭州安誉科技有限公司 | 2021-06-08 | — | — | CN | disclosed |