Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 6/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 5/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19046440 | 0.69 | IRAK4 (0.46) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL2366486 | 0.69 | ADRB1 (0.57) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL11296687 | 0.66 | HTR3A (0.46) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL470221 | 0.66 | ADRB1 (0.47) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL6128525 | 0.65 | MAPT (0.69) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL17884970 | 0.65 | ADRB1 (0.53) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL30609616 | 0.65 | ADRB1 (0.53) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL30609659 | 0.65 | ADRB1 (0.52) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL17884851 | 0.65 | ADRB1 (0.52) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL25886109 | 0.63 | FLT3 (0.48) | HTR3AHTR3EHTR3BHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-112867712-A | Carboxamides as ubiquitin-specific protease inhibitors | 瓦洛早期发现股份有限公司 | 2021-05-28 | — | — | CN | disclosed |