Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28568004 | 1.00 | USP30 (0.39) | USP30BACE1KCNH2DPP4MAPT | |
| SCHEMBL21704066 | 0.86 | GPR119 (0.40) | KCNH2DPP4MAPTTHRBKDM4E | |
| SCHEMBL21686014 | 0.85 | MAPK1 (0.34) | MAPTKDM4EALDH1A1 | |
| SCHEMBL20722741 | 0.85 | MAPK1 (0.34) | MAPTKDM4EALDH1A1 | |
| SCHEMBL21686015 | 0.85 | MAPK1 (0.34) | MAPTKDM4EALDH1A1 | |
| SCHEMBL30059886 | 0.80 | MAPT (0.42) | DPP4MAPTTHRBKDM4EKIT | |
| SCHEMBL30061814 | 0.80 | MAPT (0.42) | DPP4MAPTTHRBKDM4EKIT | |
| SCHEMBL21704014 | 0.80 | MAPT (0.42) | DPP4MAPTTHRBKDM4EKIT | |
| SCHEMBL20732122 | 0.80 | MAPT (0.42) | DPP4MAPTTHRBKDM4EKIT | |
| SCHEMBL28565689 | 0.78 | BACE1 (0.47) | BACE1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-112867712-A | Carboxamides as ubiquitin-specific protease inhibitors | 瓦洛早期发现股份有限公司 | 2021-05-28 | — | — | CN | disclosed |