Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28573737 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KMT2ASOS1PKMPOLB | |
| SCHEMBL28915327 | 0.98 | ALDH1A1 (0.46) | ALDH1A1KMT2ASOS1PKMPOLB | |
| SCHEMBL28582745 | 0.94 | ALDH1A1 (0.47) | ALDH1A1KMT2ASOS1PKMPOLB | |
| SCHEMBL28568443 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KMT2ASOS1PKMPOLB | |
| SCHEMBL28582754 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KMT2ASOS1PKMPOLB | |
| SCHEMBL28570815 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KMT2ASOS1PKMPOLB | |
| SCHEMBL28574994 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KMT2ASOS1PKMPOLB | |
| SCHEMBL1228686 | 0.75 | ALDH1A1 (0.43) | ALDH1A1KMT2ASOS1PKMPOLB | |
| SCHEMBL19664970 | 0.73 | ALDH1A1 (0.43) | ALDH1A1KMT2ASOS1PKMPOLB | |
| SCHEMBL28281549 | 0.73 | L3MBTL1 (0.47) | ALDH1A1PKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109336944-B | Tripterine imidazole derivative and preparation method and application thereof | 中国药科大学 | 2021-04-27 | — | — | CN | disclosed |