Sugi Predict

Sugi Predict / Compounds / SCHEMBL28568514

SCHEMBL28568514

SCHEMBL28568514

O=C1C=CC(=O)N1c1cccc2c1[nH]c1ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TLR9 Q9NR96 1/20 0.52
▸ KIF11 P52732 4/20 0.47
▸ MGLL Q99685 9/20 0.44
▸ ALDH1A1 P00352 3/20 0.43
▸ GPR3 P46089 2/20 0.43
▸ HSD17B10 Q99714 2/20 0.43
▸ KDM4E B2RXH2 2/20 0.43
▸ LMNA P02545 2/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ TNKS O95271 1/20 0.43
▸ CYP1A2 P05177 1/20 0.43
▸ PARP1 P09874 1/20 0.43
▸ BLM P54132 1/20 0.43
▸ PMP22 Q01453 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ PARP15 Q460N3 1/20 0.43
▸ TNKS2 Q9H2K2 1/20 0.43
▸ POLB P06746 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42
▸ GABRP O00591 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28823924 0.82 POLB (0.56) KIF11ALDH1A1GPR3HSD17B10KDM4E
SCHEMBL28370790 0.77 KIF11 (0.47) KIF11ALDH1A1GPR3HSD17B10KDM4E
SCHEMBL27614146 0.76 MEN1 (0.55) KIF11ALDH1A1KDM4EMEN1KMT2A
SCHEMBL28670278 0.75 KIF11 (0.46) KIF11ALDH1A1GPR3HSD17B10KDM4E
SCHEMBL29152722 0.75 KIF11 (0.46) KIF11ALDH1A1GPR3HSD17B10KDM4E
SCHEMBL27568785 0.74 KIF11 (0.52) KIF11ALDH1A1GPR3HSD17B10KDM4E
SCHEMBL31179969 0.73 TLR9 (0.68) TLR9MGLLALDH1A1POLBTDP1
SCHEMBL3277562 0.73 TLR9 (0.68) TLR9MGLLALDH1A1POLBTDP1
Pavettine SCHEMBL17534940 0.73 MGLL (0.46) KIF11MGLLALDH1A1CYP1A2HPGD
SCHEMBL30572810 0.72 KIF11 (0.50) KIF11ALDH1A1GPR3HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114539266-A Maleimidocarbazole compound and synthesis method thereof 湘潭大学 2022-05-27 — — CN claimed
CN-112939984-B Maleimidocarbazole compounds, and preparation method and application thereof 浙江工业大学 2022-05-13 — — CN claimed
CN-112939984-A Maleimidocarbazole compounds, and preparation method and application thereof 浙江工业大学 2021-06-11 — — CN claimed
CN-114539266-A Maleimidocarbazole compound and synthesis method thereof 湘潭大学 2022-05-27 — — CN disclosed
CN-114539266-A Maleimidocarbazole compound and synthesis method thereof 湘潭大学 2022-05-27 — — CN disclosed
CN-112939984-B Maleimidocarbazole compounds, and preparation method and application thereof 浙江工业大学 2022-05-13 — — CN disclosed
CN-112939984-B Maleimidocarbazole compounds, and preparation method and application thereof 浙江工业大学 2022-05-13 — — CN disclosed
CN-112939984-B Maleimidocarbazole compounds, and preparation method and application thereof 浙江工业大学 2022-05-13 — — CN disclosed
CN-110041338-B Bis-indole maleimide compound with anti-tumor activity and application thereof 贵州省中国科学院天然产物化学重点实验室 2021-11-30 — — CN disclosed
CN-112939984-A Maleimidocarbazole compounds, and preparation method and application thereof 浙江工业大学 2021-06-11 — — CN disclosed
CN-112939984-A Maleimidocarbazole compounds, and preparation method and application thereof 浙江工业大学 2021-06-11 — — CN disclosed
CN-112939984-A Maleimidocarbazole compounds, and preparation method and application thereof 浙江工业大学 2021-06-11 — — CN disclosed