SCHEMBL28568534

SCHEMBL28568534

Cn1cc(C(=O)C(=O)O)c(=O)[nH]c1=O.O=C(O)C(=O)c1c[nH]c(=O)[nH]c1=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.35
CYP2C9 P11712 2/20 0.35
MAPT P10636 2/20 0.35
GAA P10253 2/20 0.35
ATAD2 Q6PL18 1/20 0.35
LMNA P02545 2/20 0.35
KDM3B Q7LBC6 1/20 0.34
HTT P42858 2/20 0.33
CYP1A2 P05177 3/20 0.33
CYP2C19 P33261 3/20 0.33
POLB P06746 1/20 0.33
MEN1 O00255 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CTSL P07711 1/20 0.32
DPYD Q12882 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP19A1 P11511 1/20 0.32
TSHR P16473 1/20 0.32
THPO P40225 1/20 0.32
MTOR P42345 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25424962 0.88 KMT2A (0.42) KMT2ACYP2C9MAPTGAALMNA
SCHEMBL119748 0.83 GAA (0.48) MAPTGAAATAD2LMNAKDM3B
SCHEMBL28535407 0.82 CRBN (0.53) KMT2AGAAATAD2LMNAKDM3B
SCHEMBL8672229 0.74 KMT2A (0.45) KMT2ACYP2C9MAPTGAAKDM3B
SCHEMBL15798719 0.70 KMT2A (0.44) KMT2ACYP2C9MAPTGAAHTT
SCHEMBL127493 0.69 KDM3B (0.64) MAPTGAAATAD2LMNAKDM3B
SCHEMBL18640387 0.67 KMT2A (0.44) KMT2AMAPTGAAATAD2LMNA
SCHEMBL23240428 0.67 BRD4 (0.49) KMT2ACYP2C9MAPTGAAHTT
SCHEMBL5060056 0.67 GAA (0.50) KMT2ACYP2C9MAPTGAAHTT
Hydrochloric Acid SCHEMBL11439523 0.67 KDM3B (0.62) MAPTGAAATAD2LMNAKDM3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113122521-B Polypeptides having lipase activity and uses thereof 丰益国际有限公司 2024-05-14 CN disclosed
CN-114401748-A Stable compositions of mRNA-loaded lipid nanoparticles and methods of preparation 川斯勒佰尔公司 2022-04-26 CN disclosed
CN-114390921-A Improved MRNA-loaded lipid nanoparticles and methods of making the same 川斯勒佰尔公司 2022-04-22 CN disclosed
CN-114126588-A Improved method for preparing MRNA-loaded lipid nanoparticles 川斯勒佰尔公司 2022-03-01 CN disclosed
CN-112839639-A Improved method for preparing mRNA loaded lipid nanoparticles 川斯勒佰尔公司 2021-05-25 CN disclosed