SCHEMBL119748

SCHEMBL119748

O=C(O)C(=O)c1c[nH]c(=O)[nH]c1=O

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.48
KDM3B Q7LBC6 1/20 0.46
LMNA P02545 3/20 0.44
DPYD Q12882 5/20 0.43
ALDH1A1 P00352 4/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MAPT P10636 2/20 0.43
ATAD2 Q6PL18 1/20 0.43
CYP19A1 P11511 1/20 0.43
TSHR P16473 1/20 0.43
THPO P40225 1/20 0.43
MTOR P42345 1/20 0.43
HTT P42858 1/20 0.43
HBB P68871 1/20 0.43
PMP22 Q01453 1/20 0.43
CYP1A2 P05177 1/20 0.38
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28568534 0.83 KMT2A (0.35) GAAKDM3BLMNADPYDALDH1A1
SCHEMBL127493 0.83 KDM3B (0.64) GAAKDM3BLMNADPYDALDH1A1
Water SCHEMBL4487821 0.81 KDM3B (0.62) GAAKDM3BLMNADPYDALDH1A1
Hydrochloric Acid SCHEMBL11439523 0.81 KDM3B (0.62) GAAKDM3BLMNADPYDALDH1A1
SCHEMBL891086 0.80 GAA (0.45) GAAKDM3BLMNADPYDALDH1A1
SCHEMBL28535407 0.80 CRBN (0.53) GAAKDM3BLMNAALDH1A1SMN1; SMN2
SCHEMBL18640387 0.77 KMT2A (0.44) GAALMNADPYDALDH1A1SMN1; SMN2
SCHEMBL190958 0.77 GAA (0.50) GAAKDM3BLMNADPYDALDH1A1
SCHEMBL6524027 0.77 GAA (0.50) GAAKDM3BLMNADPYDALDH1A1
SCHEMBL1210894 0.77 GAA (0.50) GAAKDM3BLMNADPYDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 865 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150211004-A1 RNAI-BASED THERAPIES FOR CARDIOMYOPATHIES, MUSCULAR DYSTROPHIES AND LAMINOPATHIES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2015-07-30 US claimed
EP-2838541-A1 RNAI-BASED THERAPIES FOR CARDIOMYOPATHIES, MUSCULAR DYSTROPHIES AND LAMINOPATHIES Agency For Science, Technology And Research (SG) 2015-02-25 EP claimed
WO-2013158046-A1 RNAI-BASED THERAPIES FOR CARDIOMYOPATHIES, MUSCULAR DYSTROPHIES AND LAMINOPATHIES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2013-10-24 WO claimed
WO-2026106695-A1 TARGETED NANOPARTICLES ENCAPSULATING WATER-SOLUBLE THERAPEUTICS, METHODS OF PRODUCTION, AND USE OPTIMEOS LIFE SCIENCES, INC. (US) 2026-05-21 WO disclosed
WO-2026103877-A1 LIPID COMPOUND AND LIPID NANOPARTICLE COMPOSITION 中生复诺健生物科技(上海)有限公司 2026-05-21 WO disclosed
WO-2026098357-A1 FREEZE-DRIED NUCLEIC ACID-LOADED LIPID NANOPARTICLE AND RECONSTITUTION METHOD THEREOF KUDO BIOTECHNOLOGY, INC. (US) 2026-05-15 WO disclosed
US-20260130987-A1 VACCINATION AGAINST PNEUMOCCOCAL AND COVID-19 INFECTIONS PFIZER INC. (US) 2026-05-14 US disclosed
WO-2026088119-A1 LIPIDATED TLR7/8 MODULATORS AS ADJUVANTS AND USES THEREOF PFIZER INC. (US) 2026-04-30 WO disclosed
US-20260109977-A1 MODIFIED RNA FOR INCREASING PROTEIN EXPRESSION TRILINK BIOTECHNOLOGIES, LLC (US) 2026-04-23 US disclosed
EP-4728076-A1 METHOD FOR STABILIZING RNA Pfizer Inc. (US) 2026-04-22 EP disclosed
US-12606814-B2 Oligonucleotide probes and uses thereof CARIS SCIENCE, INC. (US) 2026-04-21 US disclosed
US-20050123977-A1 Assay and treatment LUDWIG INSTITUTE FOR CANCER RESEARCH 2005-06-09 US disclosed
WO-2005051431-A1 COLLOIDAL DELIVERY SYSTEM FOR BIOLOGICAL THERAPEUTIC AGENTS THE UNIVERSITY OF YORK (GB) 2005-06-09 WO disclosed
EP-1509624-A2 MET/FRET BASED METHOD OF TARGET NUCLEIC ACID DETECTION WHEREBY THE DONOR/ACCEPTOR MOIETIES ARE ON COMPLEMENTARY STRANDS SECRETARY, DEPARTMENT OF ATOMIC ENERGY (IN) 2005-03-02 EP disclosed
WO-2005014645-A2 PEDF-R RECEPTOR AND USES THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2005-02-17 WO disclosed
US-20040235171-A1 Silencing of gene expression by sirna UNIVERSITY OF YORK, THE (GB) 2004-11-25 US disclosed
WO-2003102239-A2 MET/FRET BASED METHOD OF TARGET NUCLEIC ACID DETECTION WHEREBY THE DONOR/ACCEPTOR MOIETIES ARE ON COMPLEMENTARY STRANDS SECRETARY, DEPARTMENT OF ATOMIC ENERGY (IN) 2003-12-11 WO disclosed
US-20030059417-A1 Methods and compositions for diagnosing and treating disorders involving angiogenesis SHEPPARD MICHAEL G (AU) 2003-03-27 US disclosed
WO-2002077219-A1 NOVEL HUMAN ASPARAGINASES AND POLYNUCLEOTIDES ENCODING THE SAME LEXICON GENETICS INCORPORATED (US) 2002-10-03 WO disclosed
EP-1197550-A2 Methods and compositions for diagnosing and treating disorders involving angiogenesis Pfizer Products Inc. (US) 2002-04-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109977-A1 MODIFIED RNA FOR INCREASING PROTEIN EXPRESSION RNGTT, RNMT, UPF1 GAA 3364/4885KDM3B 721/4885LMNA 337/4885
US-20260130987-A1 VACCINATION AGAINST PNEUMOCCOCAL AND COVID-19 INFECTIONS SARS1, CD14, PYCARD GAA 3633/4885KDM3B 4627/4885LMNA 2200/4885
US-12606814-B2 Oligonucleotide probes and uses thereof CD63, FLT4, NCL GAA 3273/4885KDM3B 4108/4885LMNA 1587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.