Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.33 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28568534 | 0.82 | KMT2A (0.35) | LMNAKMT2AALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL119748 | 0.80 | GAA (0.48) | LMNAALDH1A1CYP1A2SMN1; SMN2GAA | |
| SCHEMBL35355 | 0.72 | — | — | |
| SCHEMBL11146460 | 0.71 | CRBN (0.95) | CRBNDDB1 | |
| SCHEMBL29256083 | 0.70 | CTSL (0.31) | CTSL | |
| SCHEMBL25424962 | 0.69 | KMT2A (0.42) | CRBNLMNAKMT2AALDH1A1CYP1A2 | |
| SCHEMBL127493 | 0.66 | KDM3B (0.64) | LMNAALDH1A1CYP1A2SMN1; SMN2GAA | |
| SCHEMBL28561591 | 0.65 | CRBN (0.80) | CRBNLMNAALDH1A1DDB1 | |
| SCHEMBL8583798 | 0.64 | ALDH1A1 (0.50) | LMNAKMT2AALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL28813571 | 0.64 | MAPT (0.46) | CRBNLMNAALDH1A1SMN1; SMN2DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272282-A | 2, 5-dioxopiperazine lipids with inserted ester, thioester, disulfide and anhydride moieties | 川斯勒佰尔公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-112638362-A | Dry powder formulations of messenger RNA | 川斯勒佰尔公司 | 2021-04-09 | — | — | CN | disclosed |
| CN-112384205-A | Messenger RNA vaccine and uses thereof | 川斯勒佰尔公司 | 2021-02-19 | — | — | CN | disclosed |