Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28706094 | 0.86 | KDM4E (0.69) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10813681 | 0.84 | KDM4E (0.74) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10813691 | 0.81 | KDM4E (0.58) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL28582925 | 0.81 | KDM4E (0.60) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL28891547 | 0.81 | KDM4E (0.68) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL30564229 | 0.79 | ALDH1A1 (0.48) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL28593271 | 0.78 | KDM4E (0.56) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL28593269 | 0.78 | KDM4E (0.56) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL28564270 | 0.78 | KDM4E (0.65) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10813489 | 0.76 | KDM4E (0.69) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112824401-B | Acrylic ketone derivative of N-acetyl gatifloxacin and preparation method and application thereof | 河南大学 | 2023-08-11 | — | — | CN | disclosed |
| CN-112824401-A | N-acetyl gatifloxacin propenone derivative and preparation method and application thereof | 河南大学 | 2021-05-21 | — | — | CN | disclosed |