Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.49 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28568727 | 0.86 | KDM4E (0.52) | KDM4EALDH1A1LMNAHSD17B10HPGD | |
| SCHEMBL28891547 | 0.86 | KDM4E (0.68) | KDM4EALDH1A1LMNAHSD17B10HPGD | |
| SCHEMBL28559532 | 0.84 | HSD17B10 (0.58) | KDM4EALDH1A1LMNAHSD17B10HPGD | |
| SCHEMBL28564270 | 0.84 | KDM4E (0.65) | KDM4EALDH1A1LMNAHSD17B10HPGD | |
| SCHEMBL10809240 | 0.82 | KDM4E (1.00) | KDM4EALDH1A1LMNAHSD17B10HPGD | |
| SCHEMBL29350842 | 0.82 | KDM4E (1.00) | KDM4EALDH1A1LMNAHSD17B10HPGD | |
| SCHEMBL10809245 | 0.80 | KDM4E (0.77) | KDM4EALDH1A1LMNAHSD17B10HPGD | |
| SCHEMBL7101103 | 0.80 | KDM4E (0.80) | KDM4EALDH1A1LMNAHSD17B10HPGD | |
| SCHEMBL825059 | 0.79 | KDM4E (0.92) | KDM4EALDH1A1LMNAHSD17B10HPGD | |
| SCHEMBL28933214 | 0.76 | KDM4E (0.73) | KDM4EALDH1A1LMNAHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111646937-B | Propenone derivative of N-acetyl ciprofloxacin and preparation method and application thereof | 河南大学 | 2022-01-21 | — | — | CN | disclosed |