Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.34 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GALR1 | P47211 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28297380 | 0.81 | KCNH2 (0.37) | KDM1AALDH1A1TSHRKCNH2SMN1; SMN2 | |
| SCHEMBL14686714 | 0.81 | MEN1 (0.37) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL738878 | 0.81 | MEN1 (0.37) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28325770 | 0.78 | ALDH1A1 (0.36) | KDM1AMAOBALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL28325760 | 0.77 | DDB1 (0.42) | KDM1AMAOBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4065116 | 0.71 | KDM1A (0.38) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL5187861 | 0.70 | MEN1 (0.36) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5877853 | 0.70 | KDM1A (0.37) | KDM1AMAOBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2756273 | 0.70 | KDM1A (0.40) | KDM1AMAOBALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL20401774 | 0.69 | KDM1A (0.43) | KDM1AMAOBALDH1A1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110372628-B | Internal sulfonamide compound and preparation method thereof | 武汉大学 | 2021-04-02 | — | — | CN | disclosed |