SCHEMBL285689

SCHEMBL285689

O[C]1CCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3138187 0.95 TSHR (0.39)
SCHEMBL1379941 0.95
SCHEMBL3146489 0.95 TSHR (0.39)
SCHEMBL1378195 0.95
SCHEMBL57874 0.95
SCHEMBL3142403 0.95 TSHR (0.39)
SCHEMBL3144028 0.95 TSHR (0.39)
SCHEMBL5041884 0.91 TSHR (0.37)
SCHEMBL127435 0.84
SCHEMBL129884 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1544 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111406077-B Copolymers of halogenated olefins and halogenated comonomers 阿科玛股份有限公司 2024-07-05 CN claimed
EP-4385980-A1 INDAZOLES AS INHIBITORS OF NAV1.8 Grünenthal GmbH (DE) 2024-06-19 EP claimed
EP-4376819-A1 USE OF SGLT-2 INHIBITORS FOR THE PREVENTION AND/OR TREATMENT OF HYPERTENSION IN NON-HUMAN MAMMALS Boehringer Ingelheim Vetmedica GmbH (DE) 2024-06-05 EP claimed
EP-4376830-A1 USE OF SGLT-2 INHIBITORS FOR THE PREVENTION AND/OR TREATMENT OF RENAL DISEASES IN NON-HUMAN MAMMALS Boehringer Ingelheim Vetmedica GmbH (DE) 2024-06-05 EP claimed
EP-4376829-A1 USE OF SGLT-2 INHIBITORS FOR THE PREVENTION AND/OR TREATMENT OF CARDIAC DISEASES IN NON-HUMAN MAMMALS EXCLUDING FELINES, IN PARTICULAR CANINES Boehringer Ingelheim Vetmedica GmbH (DE) 2024-06-05 EP claimed
CN-118076602-A Heteroaryl-acetylenes, pharmaceutical compositions thereof and their therapeutic uses 嘉兴优博生物技术有限公司 2024-05-24 CN claimed
US-20240140915-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS VIVIDION THERAPEUTICS, INC. 2024-05-02 US claimed
CN-117843634-A SIK inhibitor and composition, preparation method and application thereof 上海美悦生物科技发展有限公司 2024-04-09 CN claimed
US-20240101546-A1 HETEROARYL-ACETYLENES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS EUBULUS BIOTHERAPEUTICS INC (CN) 2024-03-28 US claimed
US-20240092765-A1 METHODS OF INHIBITING KINASES INSILICO MEDICINE IP LIMITED (HK) 2024-03-21 US claimed
EP-0635014-A1 INDOLE DERIVATIVES AS 5-HT1-LIKE AGONISTS. PFIZER LTD (GB) 1995-01-25 EP claimed
WO-1993021177-A1 INDOLE DERIVATIVES AS 5-HT1-LIKE AGONISTS PFIZER LIMITED (GB) 1993-10-28 WO claimed
EP-0550113-A2 Triazolopyrimidine derivatives with fungicidal activity SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-07-07 EP claimed
US-5064854-A 3,4-DISUBSTITUTED PHENYL HETEROCYCLES AND THEIR USE SCHERING AKTIENGESELLSCHAFT (DE) 1991-11-12 US claimed
EP-0078158-B1 NOVEL ALKANE AND ALKENE DERIVATIVES AND THEIR PREPARATION AND USE Farmos Group Ltd. (FI) 1986-09-10 EP claimed
US-4556677-A ESTROGENIC, ANTIESTROGENIC, PROGESTANIC, ANTITUMOR AGENTS FARMOS GROUP LTD. (FI) 1985-12-03 US claimed
EP-0078158-A2 Novel alkane and alkene derivatives and their preparation and use Farmos Group Ltd. (FI) 1983-05-04 EP claimed
US-4044074-A Flame retardant polycarboxy alkyl and aryl phosphonates STAUFFER CHEMICAL COMPANY (US) 1977-08-23 US claimed
US-3984465-A DIURETIC, SALURETIC AND URICOSURIC MERCK & CO., INC. (US) 1976-10-05 US claimed
US-3974212-A DIURETIC, SALURETIC, URICOSURIC MERCK & CO., INC. (US) 1976-08-10 US claimed