SCHEMBL3144028

SCHEMBL3144028

O[C]1CCCCCCCCC1

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
CASP1 P29466 1/20 0.39
TRIM24 O15164 2/20 0.38
TRIM33 Q9UPN9 2/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3138187 1.00 TSHR (0.39) TSHRCASP1TRIM24TRIM33ALDH1A1
SCHEMBL1379941 1.00
SCHEMBL3142403 1.00 TSHR (0.39) TSHRCASP1TRIM24TRIM33ALDH1A1
SCHEMBL3146489 1.00 TSHR (0.39) TSHRCASP1TRIM24TRIM33ALDH1A1
SCHEMBL57874 1.00
SCHEMBL1378195 1.00
SCHEMBL5041884 0.96 TSHR (0.37) TSHRCASP1TRIM24TRIM33ALDH1A1
SCHEMBL285689 0.95
SCHEMBL28397186 0.86
SCHEMBL127435 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8455690-B2 Method for producing arylhydroxylamine WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2013-06-04 US disclosed
US-20100113830-A1 METHOD FOR PRODUCING ARYLHYDROXYLAMINE WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-05-06 US disclosed
EP-2154125-A1 METHOD FOR PRODUCING ARYLHYDROXYLAMINE Wako Pure Chemical Industries, Ltd. (JP) 2010-02-17 EP disclosed
US-7618914-B2 Method for producing hydroxylamine compound using platinum catalyst fixed on ion-exchange resin WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2009-11-17 US disclosed
US-20060106254-A1 Method for producing hydroxylamine compound using platinum catalyst fixed on ion-exchange resin FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2006-05-18 US disclosed
EP-1593668-A1 METHOD FOR PRODUCING HYDROXYLAMINE COMPOUND USING PLATINUM CATALYST FIXED ON ION EXCHANGE RESIN Wako Pure Chemical Industries, Ltd. (JP) 2005-11-09 EP disclosed
US-4129586-A Peroxide free radical initiators containing ultraviolet light stabilizing groups PENNWALT CORPORATION (US) 1978-12-12 US disclosed
US-4055714-A POLYMERIZATION CATALYSTS PENNWALT CORPORATION (US) 1977-10-25 US disclosed
US-4045427-A POLYMERIZATION CATALYSTS PENNWALT CORPORATION (US) 1977-08-30 US disclosed
US-4045426-A POLYMERIZATION CATALYSTS PENNWALT CORPORATION (US) 1977-08-30 US disclosed
US-4042773-A REACTION WITH POLYMERS PENNWALT CORPORATION (US) 1977-08-16 US disclosed
US-3956269-A POLYMERIZATION CATALYSTS PENNWALT CORPORATION (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100113830-A1 METHOD FOR PRODUCING ARYLHYDROXYLAMINE PAH, APEH, HPD TSHR 2790/4885CASP1 1551/4885TRIM24 4018/4885
US-20060106254-A1 Method for producing hydroxylamine compound using platinum catalyst fixed on ion-exchange resin HNMT, HRH4, HRH3 TSHR 956/4885CASP1 4552/4885TRIM24 2063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.