Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28421869 | 1.00 | TSHR (0.50) | TSHRLMNADNM1MAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL28066270 | 1.00 | TSHR (0.50) | TSHRLMNADNM1MAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL727127 | 1.00 | TSHR (0.50) | TSHRLMNADNM1MAPTNPSR1 | |
| SCHEMBL9772649 | 0.98 | TSHR (0.47) | TSHRLMNADNM1MAPTNPSR1 | |
| SCHEMBL27943905 | 0.98 | TSHR (0.47) | TSHRLMNADNM1MAPTNPSR1 | |
| Bromide SCHEMBL23923504 | 0.97 | TSHR (0.46) | TSHRLMNADNM1MAPTRAD52 | |
| Bromide SCHEMBL28483715 | 0.97 | TSHR (0.46) | TSHRLMNADNM1MAPTRAD52 | |
| Bromide SCHEMBL28559975 | 0.97 | TSHR (0.46) | TSHRLMNADNM1MAPTRAD52 | |
| Bromide SCHEMBL11689756 | 0.97 | TSHR (0.46) | TSHRLMNADNM1MAPTRAD52 | |
| Bromide SCHEMBL28559972 | 0.97 | TSHR (0.46) | TSHRLMNADNM1MAPTRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986448-A | Star-structured integrated thickener and preparation method and application thereof | 中国石油天然气集团有限公司 | 2024-05-07 | — | — | CN | claimed |
| CN-117986448-A | Star-structured integrated thickener and preparation method and application thereof | 中国石油天然气集团有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-112898477-A | Preparation method and application of nano-silica modified soap-free fluorine-free cationic polyacrylate waterproof agent | 浙江工业职业技术学院 | 2021-06-04 | — | — | CN | disclosed |