SCHEMBL28569068

SCHEMBL28569068

B.O=C1C=CC(=O)C(c2cccc3c2ccc2ccccc23)=C1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.54
CYP1A2 P05177 2/20 0.54
CYP2C9 P11712 2/20 0.54
CYP2C19 P33261 2/20 0.54
MEN1 O00255 1/20 0.54
USP2 O75604 1/20 0.54
LMNA P02545 1/20 0.54
TP53 P04637 1/20 0.54
CYP2D6 P10635 1/20 0.54
HPGD P15428 1/20 0.54
ALOX12 P18054 1/20 0.54
MAPK1 P28482 1/20 0.54
KMT2A Q03164 1/20 0.54
HIF1A Q16665 1/20 0.54
PTPN1 P18031 1/20 0.50
HPRT1 P00492 1/20 0.47
MAOA P21397 2/20 0.46
MAOB P27338 2/20 0.46
HKDC1 Q2TB90 2/20 0.44
CCR6 P51684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL51777 1.00 ALDH1A1 (0.54) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL2380017 1.00 ALDH1A1 (0.54) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
Water SCHEMBL28578882 0.98 ALDH1A1 (0.53) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL28123484 0.98 ALDH1A1 (0.53) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
Boric Acid SCHEMBL28369500 0.94 CYP1A2 (0.49) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL197980 0.91 PTPN1 (0.59) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
Alcohol SCHEMBL28567799 0.91 ALDH1A1 (0.47) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL28191302 0.90 PTPN1 (0.57) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL28461699 0.85 PTPN1 (0.45) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL27561476 0.84 PTPN1 (0.51) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112961176-B Preparation method of boron-dioxygen ring neutral radical compound 南京大学 2022-05-17 CN disclosed
CN-112961176-A Preparation method of boron-dioxygen ring neutral radical compound 南京大学 2021-06-15 CN disclosed