SCHEMBL2380017

SCHEMBL2380017

O=C1C=CC(=O)C(c2cccc3c2ccc2c4ccccc4ccc32)=C1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.54
CYP1A2 P05177 2/20 0.54
CYP2C9 P11712 2/20 0.54
CYP2C19 P33261 2/20 0.54
MEN1 O00255 1/20 0.54
USP2 O75604 1/20 0.54
LMNA P02545 1/20 0.54
TP53 P04637 1/20 0.54
CYP2D6 P10635 1/20 0.54
HPGD P15428 1/20 0.54
ALOX12 P18054 1/20 0.54
MAPK1 P28482 1/20 0.54
KMT2A Q03164 1/20 0.54
HIF1A Q16665 1/20 0.54
PTPN1 P18031 1/20 0.50
HPRT1 P00492 1/20 0.47
MAOA P21397 2/20 0.46
MAOB P27338 2/20 0.46
HKDC1 Q2TB90 2/20 0.44
CCR6 P51684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL51777 1.00 ALDH1A1 (0.54) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL28569068 1.00 ALDH1A1 (0.54) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
Water SCHEMBL28578882 0.98 ALDH1A1 (0.53) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL28123484 0.98 ALDH1A1 (0.53) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
Boric Acid SCHEMBL28369500 0.94 CYP1A2 (0.49) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL197980 0.91 PTPN1 (0.59) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
Alcohol SCHEMBL28567799 0.91 ALDH1A1 (0.47) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL28191302 0.90 PTPN1 (0.57) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL28461699 0.85 PTPN1 (0.45) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL27561476 0.84 PTPN1 (0.51) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140234827-A1 SSAT mRNA TRANSLATION REPRESSION AND ACTIVATION TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2014-08-21 US claimed
WO-2013033597-A1 SSAT MRNA TRANSLATION REPRESSION AND ACTIVATION TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2013-03-07 WO claimed
US-20110224141-A1 METHODS AND RELATED COMPOSITIONS FOR THE TREATMENT OF CANCER STC.UNM (US) 2011-09-15 US claimed
WO-2009148623-A2 METHODS AND RELATED COMPOSITIONS FOR THE TREATMENT OF CANCER STC.UNM (US) 2009-12-10 WO claimed
EP-3854862-A1 PROCESS FOR PRODUCING LIQUID HYDROCARBONS Steeper Energy ApS (DK) 2021-07-28 EP disclosed
EP-3848437-A1 PROCESS AND APPARATUS FOR PRODUCING LIQUID HYDROCARBONS Steeper Energy ApS (DK) 2021-07-14 EP disclosed
EP-2718402-B1 PROCESS FOR PRODUCING LIQUID HYDROCARBON STEEPER ENERGY APS (DK) 2021-05-26 EP disclosed
EP-2718404-B1 PROCESS FOR PRODUCING LIQUID HYDROCARBONS STEEPER ENERGY APS (DK) 2021-01-27 EP disclosed
EP-2718403-B1 PROCESS FOR PRODUCING LIQUID HYDROCARBON STEEPER ENERGY APS (DK) 2021-01-06 EP disclosed
EP-2718401-B1 PROCESS FOR PRODUCING LIQUID HYDROCARBON STEEPER ENERGY APS (DK) 2020-12-16 EP disclosed
US-10174260-B2 Process and apparatus for producing liquid hydrocarbon STEEPER ENERGY APS (DK) 2019-01-08 US disclosed
US-10150920-B2 Process for producing liquid hydrocarbon STEEPER ENERGY APS (DK) 2018-12-11 US disclosed
WO-2002057492-A1 METHODS AND COMPOSITIONS FOR DETECTING POLYNUCLEOTIDE DUPLEX DAMAGE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2002-07-25 WO disclosed
US-6306601-B1 CONTACTING DUPLEX POLYNUCLEOTIDE WITH DETECTABLE HINDERED INTERCALATING COMPOUND WHICH CAN ONLY INSERT AT DAMAGE OR ERROR, THEN DETECTING INTERCALATION THE CALIFORNIA INSTITUTE OF TECHNOLOGY 2001-10-23 US disclosed
US-6031098-A Detection and treatment of duplex polynucleotide damage CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2000-02-29 US disclosed
US-4748099-A Process for forming printing plate using an electrophotographic material for obtaining toner image KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1988-05-31 US disclosed
US-4216078-A Hydrogenation of petroleum liquids using quinone catalysts EXXON RESEARCH & ENGINEERING CO. (US) 1980-08-05 US disclosed
US-4051012-A DISTILLATION, HYDROGENATION, CIRCULATION EXXON RESEARCH & ENGINEERING CO. (US) 1977-09-27 US disclosed
US-4049536-A FORMING A SLURRY OF COAL, A SOLVENT, AND AN O-QUINONE; CONTACTING WITH HYDROGEN EXXON RESEARCH & ENGINEERING CO. (US) 1977-09-20 US disclosed
US-4049537-A SLURRYING COAL, SOLVENT, AND A QUINONE, CONTACTING WITH HYDROGEN EXXON RESEARCH & ENGINEERING CO. (US) 1977-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140234827-A1 SSAT mRNA TRANSLATION REPRESSION AND ACTIVATION RNMT, RNGTT, SRM ALDH1A1 1038/4885CYP1A2 4612/4885CYP2C9 4706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.