Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 6/20 | 0.63 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | CFTR | P13569 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28579575 | 0.84 | NPC1 (0.72) | NR4A2CREBBPMEN1KMT2ANPC1 | |
| SCHEMBL92374 | 0.81 | NPC1 (0.61) | NR4A2CREBBPMEN1KMT2ANPC1 | |
| SCHEMBL92355 | 0.81 | KMT2A (0.67) | NR4A2CREBBPMEN1KMT2ANPC1 | |
| SCHEMBL20567514 | 0.79 | NPC1 (0.65) | NR4A2CREBBPMEN1KMT2ANPC1 | |
| SCHEMBL31010176 | 0.79 | NPC1 (0.65) | NR4A2CREBBPMEN1KMT2ANPC1 | |
| SCHEMBL30031033 | 0.79 | NR4A2 (1.00) | NR4A2CREBBPMEN1KMT2ARAB9A | |
| SCHEMBL1093530 | 0.79 | NR4A2 (1.00) | NR4A2CREBBPMEN1KMT2ARAB9A | |
| SCHEMBL28572431 | 0.78 | NR4A2 (0.61) | NR4A2CREBBPMEN1KMT2ANPC1 | |
| SCHEMBL92571 | 0.78 | NPC1 (0.57) | NR4A2CREBBPMEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL28254334 | 0.77 | NR4A2 (0.97) | NR4A2CREBBPMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004187-B | Compound with function of inhibiting activity of organic anion transporter 1, preparation method and application | 沈阳药科大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-113004187-A | Compound with function of inhibiting activity of organic anion transporter 1, preparation method and application | 沈阳药科大学 | 2021-06-22 | — | — | CN | disclosed |