Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 4/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.39 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23375845 | 1.00 | KLK5 (0.47) | KLK5CTSSCTSKTACR1ACE | |
| SCHEMBL10759759 | 0.88 | KLK5 (0.47) | KLK5CTSSCTSKTACR1ACE | |
| SCHEMBL21029360 | 0.88 | KLK5 (0.47) | KLK5CTSSCTSKTACR1ACE | |
| SCHEMBL1055585 | 0.88 | ACE (0.52) | CTSSCTSKACECTSLCTSB | |
| SCHEMBL2263756 | 0.88 | ACE (0.52) | CTSSCTSKACECTSLCTSB | |
| SCHEMBL12294697 | 0.88 | CTSS (0.44) | CTSSCTSKTACR1ACECTSL | |
| SCHEMBL13252065 | 0.87 | KLK5 (0.46) | KLK5CTSSCTSKTACR1ACE | |
| SCHEMBL1061605 | 0.87 | KLK5 (0.48) | KLK5CTSSCTSKTACR1ACE | |
| SCHEMBL1061604 | 0.87 | KLK5 (0.48) | KLK5CTSSCTSKTACR1ACE | |
| SCHEMBL1056766 | 0.86 | KLK5 (0.45) | KLK5CTSSCTSKTACR1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867705-A | Opioid receptor modulators and products and methods related thereto | 埃皮欧黛公司 | 2021-05-28 | — | — | CN | disclosed |