Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.44 |
| ▸ | CTSK | P43235 | 3/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.39 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2263756 | 0.89 | ACE (0.52) | CTSSCTSKACEPPARAPPARG | |
| SCHEMBL1055585 | 0.89 | ACE (0.52) | CTSSCTSKACEPPARAPPARG | |
| SCHEMBL23375845 | 0.88 | KLK5 (0.47) | CTSSCTSKACEPPARACTSL | |
| SCHEMBL28569264 | 0.88 | KLK5 (0.47) | CTSSCTSKACEPPARACTSL | |
| SCHEMBL13316851 | 0.86 | CTSS (0.40) | CTSSCTSKACEPPARAPPARG | |
| SCHEMBL18257879 | 0.83 | CA1 (0.41) | CTSSCTSKMAP1LC3BMAP1LC3ATACR1 | |
| SCHEMBL10421355 | 0.83 | CTSS (0.47) | CTSSCTSKACEPPARACTSL | |
| SCHEMBL10421354 | 0.83 | CTSS (0.47) | CTSSCTSKACEPPARACTSL | |
| SCHEMBL23192536 | 0.82 | NPY4R (0.44) | — | |
| SCHEMBL25469278 | 0.82 | CTSK (0.44) | CTSSCTSKMAPTTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011104649-A1 | PEPTIDE ANALOGUES | PFIZER LIMITED (GB) | 2011-09-01 | — | — | WO | disclosed |