Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.67 |
| ▸ | FAAH | O00519 | 5/20 | 0.64 |
| ▸ | NAAA | Q02083 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.60 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.60 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | POLA1 | P09884 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28279281 | 1.00 | CASP2 (0.67) | CASP2FAAHNAAAL3MBTL1EPHX2 | |
| SCHEMBL9118774 | 1.00 | CASP2 (0.67) | CASP2FAAHNAAAL3MBTL1EPHX2 | |
| SCHEMBL14073969 | 1.00 | CASP2 (0.67) | CASP2FAAHNAAAL3MBTL1EPHX2 | |
| SCHEMBL8576702 | 1.00 | CASP2 (0.67) | CASP2FAAHNAAAL3MBTL1EPHX2 | |
| SCHEMBL9118282 | 1.00 | CASP2 (0.67) | CASP2FAAHNAAAL3MBTL1EPHX2 | |
| SCHEMBL23052003 | 1.00 | CASP2 (0.67) | CASP2FAAHNAAAL3MBTL1EPHX2 | |
| SCHEMBL6584132 | 1.00 | CASP2 (0.67) | CASP2FAAHNAAAL3MBTL1EPHX2 | |
| SCHEMBL28576359 | 0.96 | FAAH (0.64) | CASP2FAAHNAAAL3MBTL1EPHX2 | |
| SCHEMBL28572453 | 0.96 | FAAH (0.64) | CASP2FAAHNAAAL3MBTL1EPHX2 | |
| SCHEMBL28279287 | 0.96 | FAAH (0.64) | CASP2FAAHNAAAL3MBTL1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109422668-B | Long-acting rasagiline prodrug and preparation method and application thereof | GUANGZHOU HENOVCOM BIOSCIENCE Co.,Ltd. (CN) | 2021-06-22 | — | — | CN | disclosed |