Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | CA7 | P43166 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11133778 | 0.89 | MEN1 (0.48) | L3MBTL1HTTALDH1A1MAPK1RAB9A | |
| SCHEMBL16758709 | 0.82 | CA1 (0.62) | CA1CA2CA7CA9CA12 | |
| SCHEMBL3978489 | 0.80 | ALDH1A1 (0.48) | CA1CA2CA7CA9CA12 | |
| SCHEMBL5619739 | 0.80 | L3MBTL1 (0.44) | CA1CA2CA7CA9CA12 | |
| SCHEMBL28896673 | 0.79 | KDM4E (0.56) | CA1CA2CA7CA9CA12 | |
| SCHEMBL1748539 | 0.78 | SMN1; SMN2 (0.55) | L3MBTL1ALDH1A1MAPK1RAB9AHTR1A | |
| SCHEMBL454111 | 0.78 | CA1 (0.81) | CA1CA2CA7CA9CA12 | |
| SCHEMBL31721271 | 0.77 | MEN1 (0.50) | HTTALDH1A1MAPK1RAB9APLAU | |
| SCHEMBL2530424 | 0.77 | KDM4E (0.53) | HTTALDH1A1MAPK1RAB9AHSD17B10 | |
| SCHEMBL11132719 | 0.77 | KDM4E (0.58) | L3MBTL1HTTALDH1A1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778215-B | 2-methoxyphenoxypyrimidine antitumor compound and preparation method and application thereof | 中国医科大学 | 2023-06-20 | — | — | CN | claimed |
| CN-112778215-A | 2-methoxyphenoxy pyrimidine antitumor compound and preparation method and application thereof | 中国医科大学 | 2021-05-11 | — | — | CN | claimed |
| CN-112778215-B | 2-methoxyphenoxypyrimidine antitumor compound and preparation method and application thereof | 中国医科大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-112778215-B | 2-methoxyphenoxypyrimidine antitumor compound and preparation method and application thereof | 中国医科大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-112778215-B | 2-methoxyphenoxypyrimidine antitumor compound and preparation method and application thereof | 中国医科大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-112778215-A | 2-methoxyphenoxy pyrimidine antitumor compound and preparation method and application thereof | 中国医科大学 | 2021-05-11 | — | — | CN | disclosed |
| CN-112778215-A | 2-methoxyphenoxy pyrimidine antitumor compound and preparation method and application thereof | 中国医科大学 | 2021-05-11 | — | — | CN | disclosed |
| CN-112778215-A | 2-methoxyphenoxy pyrimidine antitumor compound and preparation method and application thereof | 中国医科大学 | 2021-05-11 | — | — | CN | disclosed |