Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 8/20 | 0.65 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28588114 | 0.91 | SMN1; SMN2 (0.55) | GRM2GABRA2GABRB2SMN1; SMN2MEN1 | |
| SCHEMBL28567634 | 0.88 | GABRA2 (0.55) | GRM2GABRA2GABRB2SMN1; SMN2MEN1 | |
| SCHEMBL28057819 | 0.82 | GRM2 (0.79) | GRM2MEN1KMT2A | |
| SCHEMBL6889759 | 0.82 | ALDH1A1 (0.61) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL22292210 | 0.80 | KDM4E (0.62) | GABRA2GABRB2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14932997 | 0.79 | GRM2 (1.00) | GRM2 | |
| SCHEMBL28883896 | 0.79 | KDM4E (0.54) | GRM2GABRA2GABRB2SMN1; SMN2ALDH1A1 | |
| SCHEMBL28958692 | 0.78 | ALDH1A1 (0.70) | GRM2GABRA2GABRB2SMN1; SMN2MEN1 | |
| SCHEMBL10955791 | 0.78 | KDM4E (0.67) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL30002312 | 0.78 | SMN1; SMN2 (0.54) | GABRA2GABRB2SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106336378-B | Preparation method of quinoline-2-formic ether series | 江西师范大学 | 2021-06-11 | — | — | CN | disclosed |