SCHEMBL28569644

SCHEMBL28569644

CCc1cc(CC)c2ccc3c(CC)cc(CC)c4ccc1c2c43

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B3 P37058 1/20 0.39
GABRA1 P14867 2/20 0.36
GABRB2 P47870 2/20 0.36
ALDH1A1 P00352 4/20 0.34
KDM4E B2RXH2 4/20 0.34
MAPT P10636 3/20 0.33
HPGD P15428 2/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
GRIN3A Q8TCU5 1/20 0.33
MEN1 O00255 2/20 0.33
POLB P06746 2/20 0.33
KMT2A Q03164 2/20 0.33
ESR1 P03372 4/20 0.32
ESR2 Q92731 4/20 0.32
ESRRB O95718 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14281968 0.83 GABRA1 (0.39) HSD17B3GABRA1GABRB2ALDH1A1KDM4E
SCHEMBL30320265 0.83 GABRA1 (0.39) HSD17B3GABRA1GABRB2ALDH1A1KDM4E
SCHEMBL9786669 0.82 HSD17B3 (0.35) HSD17B3
SCHEMBL17699137 0.78 ATM (0.35) HSD17B3GABRA1GABRB2ALDH1A1KDM4E
SCHEMBL30982344 0.73 ALDH1A1 (0.55) ALDH1A1KDM4EMAPTHPGDMEN1
SCHEMBL5442460 0.73 CYP1B1 (0.34) HSD17B3GABRA1GABRB2ALDH1A1HPGD
SCHEMBL28174921 0.73 MEN1 (0.35) HSD17B3GABRA1GABRB2ALDH1A1KDM4E
SCHEMBL3205225 0.73 GRIN2D (0.50) GABRA1GABRB2GRIN2DGRIN3BGRIN1
SCHEMBL28873788 0.72 CYP3A4 (0.44) ALDH1A1KDM4EMAPTHPGDPOLB
SCHEMBL5749079 0.72 KMT2A (0.41) ALDH1A1KDM4EMAPTHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114653344-A Triazole gel material, preparation method thereof and application of triazole gel material in adsorption of organic pollutants 中山大学 2022-06-24 CN claimed
CN-113603716-A Polycyclic aromatic hydrocarbon silane coupling agent with strong fluorescence characteristic and green efficient preparation and application thereof 山东硅科新材料有限公司 2021-11-05 CN disclosed
CN-109762085-B Compression-resistant polyaryne nanosheet and preparation method thereof 中国科学院合肥物质科学研究院 2021-06-01 CN disclosed