SCHEMBL28569692

SCHEMBL28569692

Clc1cc(Cl)c2c(c1)c1ccccc1n2-c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.55
KDM4E B2RXH2 1/20 0.55
ATM Q13315 1/20 0.55
MAT2A P31153 2/20 0.41
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
LMNA P02545 1/20 0.39
MAPK8 P45983 2/20 0.38
MAPK9 P45984 1/20 0.38
RORC P51449 1/20 0.36
DNMT1 P26358 3/20 0.36
ALDH1A1 P00352 2/20 0.36
TSHR P16473 1/20 0.36
EDNRA P25101 1/20 0.36
IL1R1 P14778 1/20 0.36
MAPK1 P28482 1/20 0.35
PGR P06401 1/20 0.35
MAPT P10636 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28913399 0.88 KDM4E (0.41) L3MBTL1KDM4EATMMAT2AALDH1A1
SCHEMBL31614620 0.84 L3MBTL1 (0.52) L3MBTL1KDM4EATMMAT2AKMT2A
SCHEMBL31614618 0.84 L3MBTL1 (0.52) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL17871554 0.84 L3MBTL1 (0.52) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL24032483 0.81 L3MBTL1 (0.57) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL27968948 0.81 KDM4E (0.61) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL17871453 0.80 KDM4E (0.47) L3MBTL1KDM4EATMMAT2AKMT2A
SCHEMBL31614626 0.80 L3MBTL1 (0.47) L3MBTL1KDM4EATMMAT2AKMT2A
SCHEMBL31614610 0.79 KDM4E (0.46) L3MBTL1KDM4EATMMAT2AKMT2A
SCHEMBL29945006 0.78 L3MBTL1 (0.57) L3MBTL1KDM4EATMMAT2AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112778343-B Boron-based organic electroluminescent material and preparation method and application thereof 武汉尚赛光电科技有限公司 2023-07-07 CN disclosed
CN-112778343-A Boron-based organic electroluminescent material and preparation method and application thereof 武汉尚赛光电科技有限公司 2021-05-11 CN disclosed
CN-112679534-A Heterocyclic organic electroluminescent material, preparation method, application and device thereof 武汉尚赛光电科技有限公司 2021-04-20 CN disclosed