SCHEMBL29945006

SCHEMBL29945006

Clc1cc(Cl)c2c3ccccc3n(-c3ccccc3)c2c1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.57
KDM4E B2RXH2 1/20 0.57
ATM Q13315 1/20 0.57
MAT2A P31153 6/20 0.52
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.40
LMNA P02545 1/20 0.40
MAPK8 P45983 3/20 0.39
MAPK9 P45984 2/20 0.39
ALDH1A1 P00352 1/20 0.38
POLB P06746 1/20 0.38
TSHR P16473 1/20 0.38
BRCA1 P38398 1/20 0.38
HSD17B10 Q99714 1/20 0.38
PRMT5 O14744 1/20 0.37
RORC P51449 1/20 0.36
IL1R1 P14778 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22112519 0.85 L3MBTL1 (0.52) L3MBTL1KDM4EATMMAT2AKMT2A
SCHEMBL24399971 0.85 L3MBTL1 (0.52) L3MBTL1KDM4EATMMAT2AKMT2A
SCHEMBL27282673 0.83 L3MBTL1 (0.53) L3MBTL1KDM4EATMMAT2AKMT2A
SCHEMBL27282675 0.83 L3MBTL1 (0.53) L3MBTL1KDM4EATMMAT2AKMT2A
SCHEMBL30432075 0.83 MAT2A (0.47) L3MBTL1KDM4EATMMAT2AKMT2A
SCHEMBL28572521 0.83 MAT2A (0.47) L3MBTL1KDM4EATMMAT2AKMT2A
SCHEMBL24032414 0.83 L3MBTL1 (0.57) L3MBTL1KDM4EATMMAT2AKMT2A
SCHEMBL15987511 0.82 L3MBTL1 (0.61) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL23502735 0.82 L3MBTL1 (0.61) L3MBTL1KDM4EATMMAT2AKMT2A
SCHEMBL31070189 0.82 L3MBTL1 (0.61) L3MBTL1KDM4EATMKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12545835-B2 Light-emitting device including heterocyclic compound and electronic apparatus including the light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2026-02-10 US disclosed
US-20220310926-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220310926-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE CRY1, NQO1, CYBA L3MBTL1 1774/4885KDM4E 3424/4885ATM 4356/4885
US-12545835-B2 Light-emitting device including heterocyclic compound and electronic apparatus including the light-emitting device CCNE2, SCO2, CCNT1 L3MBTL1 413/4885KDM4E 4003/4885ATM 3966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.