SCHEMBL28570239

SCHEMBL28570239

CC(C)(c1ccccc1)c1ccccc1I

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
ESR1 P03372 3/20 0.45
ESR2 Q92731 3/20 0.45
CYP3A4 P08684 1/20 0.45
MAPK1 P28482 1/20 0.39
TAAR1 Q96RJ0 1/20 0.37
ALOX15 P16050 1/20 0.37
NR3C2 P08235 3/20 0.36
KCNN4 O15554 3/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2199266 0.83 ALDH1A1 (0.54) ALDH1A1ESR1ESR2CYP3A4MAPK1
SCHEMBL13714189 0.78 ALDH1A1 (0.39) ALDH1A1ESR1ESR2CYP3A4MAPK1
SCHEMBL4056758 0.78 CNR1 (0.41) ALDH1A1ESR1ESR2CYP3A4MAPK1
SCHEMBL26120875 0.76 ALDH1A1 (0.48) ALDH1A1ESR1ESR2CYP3A4MAPK1
SCHEMBL29720793 0.75 ALDH1A1 (0.50) ALDH1A1TAAR1ALOX15MAPTSMN1; SMN2
SCHEMBL2876002 0.75 ALDH1A1 (0.50) ALDH1A1TAAR1ALOX15MAPTSMN1; SMN2
SCHEMBL9421204 0.74 ESR1 (0.46) ALDH1A1ESR1ESR2CYP3A4MAPK1
Bicarbonate SCHEMBL28317859 0.74 ALDH1A1 (0.52) ALDH1A1ESR1ESR2CYP3A4MAPK1
SCHEMBL14910456 0.74 ESR1 (0.70) ALDH1A1ESR1ESR2CYP3A4MAPK1
SCHEMBL35881 0.74 ESR1 (0.70) ALDH1A1ESR1ESR2CYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112794833-B Blue light dye compound and application thereof 石家庄诚志永华显示材料有限公司 2023-12-26 CN disclosed
CN-112794804-B Spirofluorene derivative and application thereof 石家庄诚志永华显示材料有限公司 2023-10-24 CN disclosed
CN-112830902-B Heterocyclic spirofluorene compounds and uses thereof 石家庄诚志永华显示材料有限公司 2023-09-29 CN disclosed
CN-112830902-A Heterocyclic spirofluorene compound and application thereof 石家庄诚志永华显示材料有限公司 2021-05-25 CN disclosed
CN-112794804-A Spirofluorene derivative and application thereof 石家庄诚志永华显示材料有限公司 2021-05-14 CN disclosed
CN-112794833-A Blue light dye compound and application thereof 石家庄诚志永华显示材料有限公司 2021-05-14 CN disclosed