Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28570415 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPK1LDHAPPARGPPARA | |
| SCHEMBL28549393 | 0.85 | LDHA (0.56) | LDHAPPARGPPARASLC6A4POLB | |
| SCHEMBL28557798 | 0.80 | ALDH1A1 (0.45) | SMN1; SMN2MAPK1LDHAPPARGPPARA | |
| SCHEMBL28558905 | 0.79 | LDHA (0.49) | LDHAPPARGPPARASLC6A4POLB | |
| SCHEMBL28558904 | 0.79 | LDHA (0.49) | LDHAPPARGPPARASLC6A4POLB | |
| SCHEMBL28558423 | 0.78 | LDHA (0.48) | SMN1; SMN2LDHAPPARGPPARASLC6A4 | |
| SCHEMBL28558424 | 0.78 | LDHA (0.48) | SMN1; SMN2LDHAPPARGPPARASLC6A4 | |
| SCHEMBL7267958 | 0.76 | LDHA (0.46) | LDHAPPARGPPARASLC6A4POLB | |
| SCHEMBL7267954 | 0.76 | LDHA (0.46) | LDHAPPARGPPARASLC6A4POLB | |
| SCHEMBL4405215 | 0.75 | LDHA (0.59) | LDHAPPARGPPARASLC6A4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107848962-B | Urea derivative or pharmacologically acceptable salt thereof | 杏林制药株式会社 | 2021-04-09 | — | — | CN | disclosed |