Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28914926 | 1.00 | HPGD (0.56) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL28571023 | 1.00 | HPGD (0.56) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL40057 | 0.90 | MEN1 (0.64) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL40056 | 0.90 | MEN1 (0.64) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL181768 | 0.90 | MEN1 (0.64) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL27963722 | 0.87 | HPGD (0.65) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| Hydrazine SCHEMBL27951659 | 0.87 | MEN1 (0.61) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL28577368 | 0.86 | HPGD (0.53) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL28574240 | 0.86 | HPGD (0.53) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL28574242 | 0.86 | HPGD (0.53) | HPGDMEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778299-B | Piperazine ureido derivatives, preparation method thereof and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-112778299-A | Piperazine ureido derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-05-11 | — | — | CN | disclosed |