Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 14/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952097 | 1.00 | MYC (0.48) | MYCRAB9AGFERHPGDALDH1A1 | |
| SCHEMBL2106226 | 0.90 | MYC (0.47) | MYCHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL2107497 | 0.85 | MYC (0.61) | MYCRAB9AGFERHPGDALDH1A1 | |
| SCHEMBL2856823 | 0.84 | MYC (0.62) | MYCRAB9ALMNA | |
| SCHEMBL2104557 | 0.82 | MYC (0.52) | MYCHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL2106204 | 0.82 | MYC (0.61) | MYCHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL2100202 | 0.82 | MYC (0.67) | MYCHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL2107082 | 0.81 | ALDH1A1 (0.47) | MYCHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL2105385 | 0.81 | MYC (0.58) | MYCHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL2105865 | 0.79 | MYC (0.51) | MYCHPGDALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1746097-B1 | 1,4-dihydropyridine-fused heterocycles, process for preparing the same, use and compositions containing them | AVENTIS PHARMA SA (FR) | 2010-01-13 | — | — | EP | disclosed |
| EP-1746097-A1 | 1,4-dihydropyridine-fused heterocycles, process for preparing the same, use and compositions containing them | Aventis Pharma S.A. (FR) | 2007-01-24 | — | — | EP | disclosed |