Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 4/20 | 0.68 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | COMT | P21964 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28567439 | 0.92 | VEGFA (0.68) | VEGFAEGLN1COMTIDO1TDO2 | |
| SCHEMBL17005844 | 0.89 | VEGFA (0.53) | VEGFAEGLN1ALDH1A1DRD2DRD4 | |
| SCHEMBL17005838 | 0.89 | ALDH1A1 (0.54) | VEGFAEGLN1ALDH1A1TP53LMNA | |
| SCHEMBL28586368 | 0.88 | VEGFA (0.71) | VEGFAEGLN1ALDH1A1LMNAMEN1 | |
| SCHEMBL28570561 | 0.87 | VEGFA (0.79) | VEGFAEGLN1IDO1TDO2IDO2 | |
| SCHEMBL28562999 | 0.87 | VEGFA (0.85) | VEGFAEGLN1IDO1TDO2IDO2 | |
| SCHEMBL4502120 | 0.87 | VEGFA (0.49) | VEGFAEGLN1ALDH1A1DRD2DRD4 | |
| SCHEMBL28567368 | 0.86 | VEGFA (0.77) | VEGFAEGLN1IDO1TDO2IDO2 | |
| SCHEMBL17005902 | 0.86 | VEGFA (0.53) | VEGFAEGLN1ALDH1A1DRD2DRD4 | |
| SCHEMBL28913769 | 0.86 | VEGFA (0.73) | VEGFAEGLN1ALDH1A1IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232120-B | Process for preparing N-benzyl-3-hydroxy-4-substituted-pyridin-2- (1H) -ones | 爱尔皮奥治疗有限公司 | 2021-01-08 | — | — | CN | disclosed |