Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM6B | O15054 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28109150 | 0.82 | ALDH1A1 (0.54) | KDM4EALDH1A1MAPTNPSR1LMNA | |
| SCHEMBL2129251 | 0.79 | SMN1; SMN2 (0.49) | KDRKDM4ETDP1ALDH1A1MAPT | |
| SCHEMBL27648140 | 0.79 | ALDH1A1 (0.49) | KDM4EALDH1A1SLC2A4MAPTMAPK1 | |
| SCHEMBL1715372 | 0.78 | KDR (0.65) | KDRKDM4EKDM6BKDM4AKDM4D | |
| SCHEMBL4431043 | 0.74 | KDM4E (0.49) | KDM4ETDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL3880000 | 0.72 | KDM4E (0.59) | KDM4ETDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL5252687 | 0.72 | KDM4E (0.59) | KDM4ETDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL258223 | 0.71 | ALDH1A1 (0.55) | KDM4ETDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL1042566 | 0.71 | SLC2A4 (0.63) | TDP1ALDH1A1SLC2A4MAPTGAA | |
| SCHEMBL1722473 | 0.71 | SMN1; SMN2 (0.57) | KDM4ETDP1ALDH1A1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108467360-B | Preparation method and intermediate of apatinib | 江苏美迪克化学品有限公司 | 2021-04-30 | — | — | CN | disclosed |