SCHEMBL258223

SCHEMBL258223

O=C(O)c1cccnc1Cc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
CYP2C9 P11712 1/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
LMNA P02545 1/20 0.55
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54
KDM4E B2RXH2 3/20 0.53
TDP1 Q9NUW8 1/20 0.53
ALOX15 P16050 2/20 0.52
TSHR P16473 2/20 0.52
CYP3A4 P08684 1/20 0.52
MAPT P10636 1/20 0.52
BLM P54132 1/20 0.52
AGER Q15109 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
NAPRT Q6XQN6 2/20 0.50
POLB P06746 1/20 0.49
DHODH Q02127 1/20 0.47
GAA P10253 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salicylic Acid SCHEMBL810603 0.92 ALDH1A1 (0.56) ALDH1A1CYP2C9SMN1; SMN2LMNANPC1
Lactic Acid SCHEMBL810781 0.89 ALDH1A1 (0.47) ALDH1A1CYP2C9SMN1; SMN2LMNANPC1
SCHEMBL158842 0.89 POLB (0.49) ALDH1A1CYP2C9SMN1; SMN2LMNANPC1
Mandelic Acid SCHEMBL6703846 0.87 LMNA (0.49) ALDH1A1CYP2C9SMN1; SMN2LMNANPC1
SCHEMBL2129407 0.87 SMN1; SMN2 (0.59) ALDH1A1SMN1; SMN2LMNAKDM4ETDP1
SCHEMBL15738996 0.87 KMT2A (0.53) ALDH1A1CYP2C9SMN1; SMN2LMNANPC1
SCHEMBL11628316 0.87 USP2 (0.54) ALDH1A1CYP2C9SMN1; SMN2LMNANPC1
SCHEMBL9869486 0.86 POLB (0.47) ALDH1A1CYP2C9SMN1; SMN2LMNANPC1
SCHEMBL2306128 0.86 SYK (0.48) ALDH1A1CYP2C9SMN1; SMN2LMNANPC1
Malic Acid SCHEMBL811048 0.86 ALDH1A1 (0.44) ALDH1A1CYP2C9SMN1; SMN2LMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118835286-A Metal material and surface treatment method thereof 栾全慧 2024-10-25 CN claimed
CN-117385427-A High-brightness zinc-nickel alloy electroplating solution and preparation method thereof 深圳市协成达科技有限公司 2024-01-12 CN claimed
CN-117248254-A Electroplating solution for improving alkaline zinc plating and zinc alloy deep plating capability and use method thereof 德锡化学(山东)有限公司 2023-12-19 CN claimed
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 CN claimed
EP-3453364-B1 HEAT GENERATOR KOBAYASHI PHARMACEUTICAL CO LTD (JP) 2022-08-24 EP claimed
CN-111593378-A Preparation of high corrosion-resistant alkaline zinc-nickel alloy electroplating solution and components of additive 常州新纪元材料科技有限公司 2020-08-28 CN claimed
CN-103510133-B A kind of carrier brightening agent and its preparation method and application Shaoguan Mei Tuowei will Chemical Co., Ltd. (CN) 2016-04-06 CN claimed
CN-103952733-A Carrier brightener precursor and carrier brightener for alkaline zinc-plating or zinc alloy electroplating solution and electroplating solution SHAOGUAN MEITUO WEIZHI CHEMICAL CO LTD 2014-07-30 CN claimed
CN-103510133-A Carrier brightening agent as well as preparation method and application thereof SHAOGUAN MEITUO WEIZHI CHEMICAL CO LTD 2014-01-15 CN claimed
WO-2007046577-A1 EXTERNAL COMPOSITION FOR HAIR GROWTH AMOREPACIFIC CORPORATION (KR) 2007-04-26 WO claimed
US-7081258-B2 Composition for promoting hair growth LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2006-07-25 US claimed
US-20040241114-A1 Hair Care and Nail Care Compositions Based on Ion-Pair Delivery System for Gender and Ethnic Selective Applications GUPTA SHYAM K (US) 2004-12-02 US claimed
US-20040228884-A1 Ion-pair delivery system for cosmetic and pharmaceutical compositions GUPTA SHYAM K (US) 2004-11-18 US claimed
US-20040185069-A1 Hydroxycitric acid derivatives for body slimming and tone firming compositions GUPTA SHYAM K (US) 2004-09-23 US claimed
US-20040092482-A1 Hydroxy acids based delivery systems for skin resurfacing and anti-aging compositions GUPTA SHYAM K (US) 2004-05-13 US claimed
EP-0300461-A2 Aromatic heterocyclic peroxyacids AUSIMONT S.p.A. (IT) 1989-01-25 EP claimed
US-12559852-B2 Composition for tin-silver alloy electroplating comprising a complexing agent BASF SE (DE) 2026-02-24 US disclosed
US-20260041109-A1 ROBUST FLAVOR EMULSIONS INT FLAVORS & FRAGRANCES INC (US) 2026-02-12 US disclosed
WO-1993005047-A1 NEW TRICYCLIC THIAZOL AND OXAZOL DERIVATES WITH ANTIVIRAL ACTION BOEHRINGER MANNHEIM GMBH (DE) 1993-03-18 WO disclosed
EP-0300461-A2 Aromatic heterocyclic peroxyacids AUSIMONT S.p.A. (IT) 1989-01-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040092482-A1 Hydroxy acids based delivery systems for skin resurfacing and anti-aging compositions CUTA, HIRA, HARS1 ALDH1A1 1928/4885CYP2C9 3151/4885SMN1; SMN2 4162/4885
US-12559852-B2 Composition for tin-silver alloy electroplating comprising a complexing agent SLC13A3, GNA11, AP3D1 ALDH1A1 3242/4885CYP2C9 1759/4885SMN1; SMN2 1385/4885
US-20260041109-A1 ROBUST FLAVOR EMULSIONS ACACA, FABP4, CUTA ALDH1A1 362/4885CYP2C9 3331/4885SMN1; SMN2 2243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.