Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | IGF1R | P08069 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.45 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.44 |
| ▸ | STK17B | O94768 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28573101 | 1.00 | PDE4B (0.50) | PDE4BPDE3ADYRK1AMEN1KMT2A | |
| SCHEMBL28571661 | 0.95 | IGF1R (0.53) | PDE4BPDE3ADYRK1AMEN1KMT2A | |
| SCHEMBL28571664 | 0.95 | IGF1R (0.53) | PDE4BPDE3ADYRK1AMEN1KMT2A | |
| SCHEMBL28915135 | 0.81 | MIF (0.49) | MEN1KMT2AMAPTLMNAGAA | |
| SCHEMBL28915136 | 0.81 | MIF (0.49) | MEN1KMT2AMAPTLMNAGAA | |
| SCHEMBL28588030 | 0.81 | KMT2A (0.58) | DYRK1AMEN1KMT2AMAPTLMNA | |
| SCHEMBL28588029 | 0.81 | KMT2A (0.58) | DYRK1AMEN1KMT2AMAPTLMNA | |
| SCHEMBL29857296 | 0.76 | MAPT (0.78) | PDE4BPDE3ADYRK1AMEN1KMT2A | |
| SCHEMBL625104 | 0.75 | DYRK1A (0.60) | DYRK1AKMT2AMAPTLMNAGAA | |
| SCHEMBL28587111 | 0.74 | EGFR (0.50) | DYRK1AMEN1KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112972441-B | Application of monocarbonyl curcumin compound in preparation of medicine for preventing and treating periodontitis | 温州医科大学附属口腔医院 | 2022-08-23 | — | — | CN | disclosed |
| CN-112972441-A | Application of monocarbonyl curcumin compound in preparation of medicine for preventing and treating periodontitis | 温州医科大学附属口腔医院 | 2021-06-18 | — | — | CN | disclosed |