Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28587113 | 1.00 | EGFR (0.50) | EGFRMAPTMEN1KMT2ANPC1 | |
| SCHEMBL625104 | 0.83 | DYRK1A (0.60) | EGFRMAPTKMT2ANPC1RAB9A | |
| SCHEMBL625103 | 0.83 | DYRK1A (0.60) | EGFRMAPTKMT2ANPC1RAB9A | |
| SCHEMBL28575414 | 0.78 | ALDH1A1 (0.56) | MAPTKMT2APKML3MBTL1PIM1 | |
| SCHEMBL28575415 | 0.78 | ALDH1A1 (0.56) | MAPTKMT2APKML3MBTL1PIM1 | |
| SCHEMBL28588029 | 0.76 | KMT2A (0.58) | MAPTMEN1KMT2ARAB9APKM | |
| SCHEMBL28915135 | 0.76 | MIF (0.49) | EGFRMAPTMEN1KMT2ANPC1 | |
| SCHEMBL28588030 | 0.76 | KMT2A (0.58) | MAPTMEN1KMT2ARAB9APKM | |
| SCHEMBL28915136 | 0.76 | MIF (0.49) | EGFRMAPTMEN1KMT2ANPC1 | |
| SCHEMBL28571661 | 0.74 | IGF1R (0.53) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112972441-A | Application of monocarbonyl curcumin compound in preparation of medicine for preventing and treating periodontitis | 温州医科大学附属口腔医院 | 2021-06-18 | — | — | CN | disclosed |