Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28915135 | 1.00 | MIF (0.49) | MIFMAOBEGFRMAPTMEN1 | |
| SCHEMBL28588030 | 0.90 | KMT2A (0.58) | MIFMAOBMAPTMEN1KMT2A | |
| SCHEMBL28588029 | 0.90 | KMT2A (0.58) | MIFMAOBMAPTMEN1KMT2A | |
| SCHEMBL28573101 | 0.81 | PDE4B (0.50) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL28571661 | 0.81 | IGF1R (0.53) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL28571664 | 0.81 | IGF1R (0.53) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL28573102 | 0.81 | PDE4B (0.50) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL625104 | 0.78 | DYRK1A (0.60) | MAOBEGFRMAPTKMT2AALDH1A1 | |
| SCHEMBL625103 | 0.78 | DYRK1A (0.60) | MAOBEGFRMAPTKMT2AALDH1A1 | |
| SCHEMBL28587111 | 0.76 | EGFR (0.50) | MAOBEGFRMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112972441-B | Application of monocarbonyl curcumin compound in preparation of medicine for preventing and treating periodontitis | 温州医科大学附属口腔医院 | 2022-08-23 | — | — | CN | disclosed |
| CN-112972441-A | Application of monocarbonyl curcumin compound in preparation of medicine for preventing and treating periodontitis | 温州医科大学附属口腔医院 | 2021-06-18 | — | — | CN | disclosed |