Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 1.00 |
| ▸ | RAB9A | P51151 | 9/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.66 |
| ▸ | HPGD | P15428 | 5/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22618530 | 0.91 | NPC1 (0.84) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL285733 | 0.88 | NPC1 (0.78) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL29575333 | 0.88 | NPC1 (0.78) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11339738 | 0.85 | NPC1 (0.74) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL28710441 | 0.85 | NPC1 (0.74) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10547901 | 0.84 | RAB9A (0.73) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11593721 | 0.84 | IGF2BP2 (0.81) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11593974 | 0.84 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11396153 | 0.84 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10938738 | 0.83 | NPC1 (0.71) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383854-B1 | WATER-SOLUBLE UV-ABSORBING COMPOUNDS AND USES THEREOF | ALCON INC (CH) | 2021-03-03 | — | — | EP | disclosed |
| US-10823983-B2 | UV-absorbing vinylic monomers and uses thereof | ALCON INC. (CH) | 2020-11-03 | — | — | US | disclosed |
| US-10823983-B2 | UV-absorbing vinylic monomers and uses thereof | ALCON INC. (CH) | 2020-11-03 | — | — | US | disclosed |
| EP-3419966-B1 | UV-ABSORBING VINYLIC MONOMERS AND USES THEREOF | ALCON INC (CH) | 2020-03-25 | — | — | EP | disclosed |
| US-10472319-B2 | Water-soluble UV-absorbing compounds and uses thereof | NOVARTIS AG (CH) | 2019-11-12 | — | — | US | disclosed |
| US-10472319-B2 | Water-soluble UV-absorbing compounds and uses thereof | NOVARTIS AG (CH) | 2019-11-12 | — | — | US | disclosed |
| US-20190256455-A1 | WATER-SOLUBLE UV-ABSORBING COMPOUNDS AND USES THEREOF | ALCON INC. (CH) | 2019-08-22 | — | — | US | disclosed |
| US-20190256455-A1 | WATER-SOLUBLE UV-ABSORBING COMPOUNDS AND USES THEREOF | ALCON INC. (CH) | 2019-08-22 | — | — | US | disclosed |
| US-10322993-B2 | Water-soluble UV-absorbing compounds and uses thereof | NOVARTIS AG (CH) | 2019-06-18 | — | — | US | disclosed |
| US-10322993-B2 | Water-soluble UV-absorbing compounds and uses thereof | NOVARTIS AG (CH) | 2019-06-18 | — | — | US | disclosed |
| US-4957818-A | COATING TO PREVENT MIGRATION OF PLASTICIZER FROM VINYL CHLORIDE RESIN | MITSUBISHI KASEI VINYL COMPANY (JP) | 1990-09-18 | — | — | US | disclosed |
| EP-0303297-A2 | Molded synthetic resin product | MITSUBISHI KASEI VINYL COMPANY (JP) | 1989-02-15 | — | — | EP | disclosed |
| EP-0134389-B1 | VINYL CHLORIDE RESIN COMPOSITION | NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) | 1988-07-27 | — | — | EP | disclosed |
| US-4709041-A | 2-(formylphenyl) benzotriazole intermediates | POLAROID CORPORATION (US) | 1987-11-24 | — | — | US | disclosed |
| US-4670490-A | CONTAINING DIESTER PLASTICIZER-MOLDING MATERIALS | NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) | 1987-06-02 | — | — | US | disclosed |
| EP-0065574-B1 | PHOTOSYNTHETIC BACTERIA CULTURE | NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) | 1986-05-21 | — | — | EP | disclosed |
| EP-0134389-A2 | Vinyl chloride resin composition | NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) | 1985-03-20 | — | — | EP | disclosed |
| US-4467035-A | Cultivation of phototrophic bacteria in the absence of ultraviolet light | NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) | 1984-08-21 | — | — | US | disclosed |
| EP-0065574-A1 | PHOTOSYNTHETIC BACTERIA CULTURE | NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) | 1982-12-01 | — | — | EP | disclosed |
| US-4235043-A | Method for cultivating algae and a covering material used therefor | Nippon Carbide Kogyo Kabashiki Kaisha (JP) | 1980-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10823983-B2 | UV-absorbing vinylic monomers and uses thereof | UACA, VCL, CRYZ | NPC1 4585/4885RAB9A 1944/4885SMN1; SMN2 4748/4885 |
| US-10472319-B2 | Water-soluble UV-absorbing compounds and uses thereof | CRYZ, UACA, XRCC5 | NPC1 4295/4885RAB9A 1365/4885SMN1; SMN2 4761/4885 |
| US-10322993-B2 | Water-soluble UV-absorbing compounds and uses thereof | CRYZ, UACA, XRCC5 | NPC1 4295/4885RAB9A 1365/4885SMN1; SMN2 4761/4885 |
| US-20190256455-A1 | WATER-SOLUBLE UV-ABSORBING COMPOUNDS AND USES THEREOF | CRYZ, UACA, XRCC5 | NPC1 4295/4885RAB9A 1365/4885SMN1; SMN2 4761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.