SCHEMBL28573302

SCHEMBL28573302

[c]1ccc(-c2ccncc2)c2occc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 2/20 0.39
TSHR P16473 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
DYRK1A Q13627 1/20 0.34
MAPT P10636 2/20 0.33
LMNA P02545 1/20 0.33
MAPK13 O15264 1/20 0.32
MAPK12 P53778 1/20 0.32
MAPK11 Q15759 1/20 0.32
PTK2 Q05397 1/20 0.32
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HTT P42858 1/20 0.31
NSD3 Q9BZ95 1/20 0.31
TP53 P04637 1/20 0.31
PKM P14618 1/20 0.31
PIK3R1 P27986 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21300575 0.82 CHRM2 (0.33)
SCHEMBL21295636 0.72 MAPK14 (0.39) MAPK14TSHRSMN1; SMN2MEN1KMT2A
SCHEMBL21295724 0.69 DYRK1A (0.41) MAPK14TSHRSMN1; SMN2MEN1KMT2A
SCHEMBL28217059 0.68 SMN1; SMN2 (0.46) MAPK14TSHRSMN1; SMN2MEN1KMT2A
SCHEMBL27542535 0.68 IMPDH2 (0.43) SMN1; SMN2MEN1KMT2ADYRK1AMAPT
SCHEMBL12892528 0.66 SMN1; SMN2 (0.62) MAPK14TSHRSMN1; SMN2MEN1KMT2A
SCHEMBL21295662 0.66 DYRK1A (0.41) MAPK14TSHRSMN1; SMN2MEN1KMT2A
SCHEMBL21295814 0.66 MAPK14 (0.39) MAPK14SMN1; SMN2MAPTLMNANPC1
SCHEMBL21295853 0.64 MAPK14 (0.37) MAPK14TSHRSMN1; SMN2MEN1KMT2A
SCHEMBL24319009 0.63 MAPK14 (0.79) MAPK14TSHRSMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed