Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18341910 | 0.75 | AKT1 (0.59) | HSD17B10AKT1CHEK1 | |
| SCHEMBL29859618 | 0.71 | HSD17B10 (0.56) | HSD17B10AKT1CHEK1 | |
| SCHEMBL3382220 | 0.71 | HSD17B10 (0.66) | HSD17B10AKT1CHEK1 | |
| SCHEMBL25780379 | 0.69 | HSD17B10 (0.49) | HSD17B10AKT1CHEK1 | |
| SCHEMBL38662484 | 0.69 | HSD17B10 (0.67) | HSD17B10AKT1CHEK1 | |
| SCHEMBL31716653 | 0.69 | HSD17B10 (0.63) | HSD17B10AKT1CHEK1 | |
| SCHEMBL25781012 | 0.69 | HSD17B10 (0.46) | HSD17B10AKT1CHEK1 | |
| SCHEMBL2406026 | 0.68 | — | — | |
| SCHEMBL3378290 | 0.67 | AKT1 (0.62) | HSD17B10AKT1CHEK1 | |
| SCHEMBL3840417 | 0.66 | HSD17B10 (0.71) | HSD17B10AKT1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214287-B | HPK1 inhibitors and methods of use thereof | 大学健康网络 | 2023-10-20 | — | — | CN | disclosed |
| CN-113214287-A | HPK1 inhibitors and methods of use thereof | 大学健康网络 | 2021-08-06 | — | — | CN | disclosed |
| CN-107922431-B | HPK1 inhibitors and methods of use thereof | 大学健康网络 | 2021-06-04 | — | — | CN | disclosed |