Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30592571 | 0.82 | HSD17B10 (0.50) | HSD17B10CHEK1MAPTAKT1KDM4E | |
| SCHEMBL3382220 | 0.80 | HSD17B10 (0.66) | HSD17B10CHEK1MAPTAKT1KDM4E | |
| SCHEMBL30592552 | 0.80 | HSD17B10 (0.47) | HSD17B10CHEK1MAPTAKT1KDM4E | |
| SCHEMBL30592547 | 0.80 | HSD17B10 (0.47) | HSD17B10CHEK1MAPTAKT1KDM4E | |
| SCHEMBL30592585 | 0.80 | HSD17B10 (0.47) | HSD17B10CHEK1MAPTAKT1KDM4E | |
| SCHEMBL30592586 | 0.80 | HSD17B10 (0.47) | HSD17B10CHEK1MAPTAKT1KDM4E | |
| SCHEMBL31716653 | 0.78 | HSD17B10 (0.63) | HSD17B10CHEK1MAPTAKT1KDM4E | |
| SCHEMBL31735534 | 0.76 | HSD17B10 (0.71) | HSD17B10CHEK1MAPTKDM4EALDH1A1 | |
| SCHEMBL3840417 | 0.76 | HSD17B10 (0.71) | HSD17B10CHEK1MAPTAKT1KDM4E | |
| SCHEMBL3840420 | 0.76 | HSD17B10 (0.71) | HSD17B10CHEK1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022188823-A1 | TRICYCLIC HPK1 INHIBITOR AND USE THEREOF | 山东轩竹医药科技有限公司 | 2022-09-15 | — | — | WO | disclosed |