⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5216740 | 0.89 | — | — | |
| SCHEMBL1338682 | 0.86 | NPC1 (0.48) | — | |
| SCHEMBL26154082 | 0.85 | — | — | |
| SCHEMBL26156229 | 0.79 | — | — | |
| SCHEMBL14150738 | 0.79 | — | — | |
| SCHEMBL15687863 | 0.79 | — | — | |
| SCHEMBL14151635 | 0.79 | SLC6A3 (0.61) | — | |
| SCHEMBL14150903 | 0.79 | SLC6A3 (0.61) | — | |
| SCHEMBL14151343 | 0.79 | — | — | |
| SCHEMBL15687862 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102321041-B | Preparation method of linezolid | BEIJING SECOND PHARMACEUTICAL CO LTD | 2013-09-25 | — | — | CN | claimed |
| CN-102321041-A | Preparation method of linezolid | BEIJING SECOND PHARMACEUTICAL CO LTD | 2012-01-18 | — | — | CN | claimed |
| WO-2011114210-A2 | PROCESSES FOR THE PREPARATION OF LINEZOLID | JUBILANT LIFE SCIENCES LIMITED (IN) | 2011-09-22 | — | — | WO | disclosed |