Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854345 | 0.92 | TSHR (0.43) | TSHRSMN1; SMN2MAPTNPSR1THRB | |
| SCHEMBL14173246 | 0.88 | ACACB (0.43) | TSHRRAB9ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL14173248 | 0.88 | ACACB (0.43) | TSHRRAB9ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL13554408 | 0.88 | MAPT (0.43) | TSHRSMN1; SMN2MAPTNPSR1THRB | |
| SCHEMBL22588946 | 0.87 | HPGD (0.42) | TSHRMAPTALDH1A1THRBACACB | |
| SCHEMBL28432324 | 0.87 | PTGS1 (0.43) | TSHRTHRBACACBLMNAGAA | |
| SCHEMBL6986550 | 0.85 | THRB (0.38) | TSHRMAPTNPSR1KDM4EALDH1A1 | |
| SCHEMBL4200257 | 0.85 | THRB (0.44) | TDP1TSHRMAPTNPSR1KDM4E | |
| SCHEMBL181492 | 0.85 | THRB (0.54) | TSHRMAPTTHRBLMNACYP2D6 | |
| SCHEMBL28440337 | 0.84 | THRB (0.37) | TSHRMAPTNPSR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641832-B | Azo compounds, polymers, and methods of preparation and use | 东莞东阳光医疗智能器件研发有限公司 | 2021-06-08 | — | — | CN | disclosed |