SCHEMBL28575205

SCHEMBL28575205

CCCCC(c1nc(N)nc(N)n1)c1[nH]c(CC)nc1C

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 7/20 0.33
TLR7 Q9NYK1 3/20 0.33
TP53 P04637 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HTR1A P08908 1/20 0.31
HTR2A P28223 1/20 0.31
HTR7 P34969 1/20 0.31
HTR6 P50406 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28559980 0.96 TLR8 (0.32) TLR8TLR7TP53L3MBTL1
SCHEMBL28577390 0.94 TLR8 (0.31) TLR8TLR7TP53L3MBTL1
SCHEMBL28566421 0.93 TP53 (0.33) TP53L3MBTL1
SCHEMBL28559985 0.87 TP53 (0.34) TP53L3MBTL1
SCHEMBL28566841 0.78 DHFR (0.37) TLR8TLR7HTR1AHTR2AHTR7
SCHEMBL28563241 0.74 DHFR (0.39) TLR8
SCHEMBL28569892 0.73 DHFR (0.41) TLR8TLR7
SCHEMBL28563229 0.70 USP2 (0.37) HTR1AHTR2AHTR7HTR6
SCHEMBL28564371 0.68 HTR7 (0.36) TLR8TLR7HTR1AHTR2AHTR7
SCHEMBL31531724 0.68 CDK1 (0.34) HTR1AHTR2AHTR7HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112724596-B Curable composition and cured product 盛势达技研株式会社 2025-04-18 CN disclosed
CN-112724596-A Curable composition and cured product 盛势达技研株式会社 2021-04-30 CN disclosed