Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.48 |
| ▸ | ST14 | Q9Y5Y6 | 8/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.47 |
| ▸ | F10 | P00742 | 11/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25016086 | 1.00 | F2 (0.48) | F2ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL25017363 | 0.94 | ST14 (0.55) | F2ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL25017931 | 0.93 | F2 (0.53) | F2ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL25016809 | 0.92 | F2 (0.49) | F2ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL25017932 | 0.92 | F2 (0.49) | F2ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL28578396 | 0.91 | F10 (0.48) | F2ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL28578395 | 0.91 | F10 (0.48) | F2ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL28583288 | 0.87 | CCR9 (0.46) | F2ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL28583287 | 0.87 | CCR9 (0.46) | F2ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL25017844 | 0.87 | ST14 (0.61) | F2ST14PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |