Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.45 |
| ▸ | ST14 | Q9Y5Y6 | 5/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.45 |
| ▸ | PLG | P00747 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 8/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28578395 | 1.00 | F10 (0.48) | F10PRSS1ST14PRSS2PRSS3 | |
| SCHEMBL28573604 | 0.92 | SMYD3 (0.47) | F10PRSS1ST14PRSS2PRSS3 | |
| SCHEMBL28573606 | 0.92 | SMYD3 (0.47) | F10PRSS1ST14PRSS2PRSS3 | |
| SCHEMBL25016086 | 0.91 | F2 (0.48) | F10PRSS1ST14PRSS2PRSS3 | |
| SCHEMBL28575219 | 0.91 | F2 (0.48) | F10PRSS1ST14PRSS2PRSS3 | |
| SCHEMBL25017363 | 0.85 | ST14 (0.55) | F10PRSS1ST14PRSS2PRSS3 | |
| SCHEMBL25017931 | 0.84 | F2 (0.53) | F10PRSS1ST14PRSS2PRSS3 | |
| SCHEMBL31689670 | 0.84 | F10 (0.45) | F10PRSS1ST14PRSS2PRSS3 | |
| SCHEMBL28583287 | 0.84 | CCR9 (0.46) | F10PRSS1ST14PRSS2PRSS3 | |
| SCHEMBL28583288 | 0.84 | CCR9 (0.46) | F10PRSS1ST14PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |