Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28902824 | 0.77 | CLK1 (0.31) | — | |
| SCHEMBL27209845 | 0.75 | PDGFRB (0.31) | — | |
| SCHEMBL29005839 | 0.75 | — | — | |
| SCHEMBL29005840 | 0.73 | AKR1B1 (0.30) | AKR1B1 | |
| SCHEMBL29885344 | 0.73 | PDPK1 (0.49) | KDM4EMPIL3MBTL1 | |
| SCHEMBL21091402 | 0.73 | PDPK1 (0.49) | KDM4EMPIL3MBTL1 | |
| SCHEMBL28564433 | 0.71 | PLK4 (0.30) | PIM1 | |
| Bromide SCHEMBL29611625 | 0.71 | PDPK1 (0.47) | KDM4EMPIL3MBTL1 | |
| Bromide SCHEMBL21839488 | 0.71 | PDPK1 (0.47) | KDM4EMPIL3MBTL1 | |
| Bromide SCHEMBL21839487 | 0.70 | PDPK1 (0.46) | KDM4EMPIL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113637005-B | KRAS inhibitors for cancer treatment | 泰励生物科技（上海）有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-117820333-A | KRAS G12C inhibitors | 伊莱利利公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-114828964-B | KRAS G12C inhibitors | 伊莱利利公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-114828964-A | KRAS G12C inhibitors | 伊莱利利公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-112805281-B | KRAS G12C inhibitors | 伊莱利利公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-113637005-A | KRAS inhibitors for cancer treatment | 泰励生物科技（上海）有限公司 | 2021-11-12 | — | — | CN | disclosed |
| CN-112805281-A | KRAS G12C inhibitors | 伊莱利利公司 | 2021-05-14 | — | — | CN | disclosed |