Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28575299 | 0.77 | PIM1 (0.33) | — | |
| SCHEMBL28902795 | 0.76 | CA2 (0.37) | — | |
| SCHEMBL30231115 | 0.76 | CA2 (0.37) | — | |
| SCHEMBL29031079 | 0.73 | PTGS2 (0.32) | — | |
| SCHEMBL30231203 | 0.73 | SMN1; SMN2 (0.58) | SMN1; SMN2 | |
| SCHEMBL28902805 | 0.73 | SMN1; SMN2 (0.58) | SMN1; SMN2 | |
| SCHEMBL28782049 | 0.72 | NPC1 (0.34) | DYRK1A | |
| SCHEMBL30622711 | 0.72 | ALDH1A1 (0.53) | SMN1; SMN2 | |
| SCHEMBL28564366 | 0.72 | MAPT (0.39) | DYRK1ASMN1; SMN2 | |
| SCHEMBL28400513 | 0.72 | ALDH1A1 (0.53) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116390923-A | Heterocyclic derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-115403575-A | Heteroaromatic ring derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-115385912-A | Pyrazinopyrazinoquinolinone derivatives, preparation method and medical application thereof | 浙江海正药业股份有限公司 | 2022-11-25 | — | — | CN | disclosed |