SCHEMBL28575336

SCHEMBL28575336

CC=CCCN(C)S(=O)(=O)c1cccs1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
SMN1; SMN2 Q16637 4/20 0.56
HPGD P15428 2/20 0.56
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.45
HSD17B10 Q99714 1/20 0.42
POLB P06746 2/20 0.42
TP53 P04637 1/20 0.41
GAA P10253 1/20 0.41
TSHR P16473 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
SQLE Q14534 2/20 0.39
NR1H3 Q13133 1/20 0.39
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28575333 1.00 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2HPGDNPC1RAB9A
SCHEMBL7212010 0.77 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2HPGDNPC1RAB9A
SCHEMBL12077803 0.76 ALDH1A1 (0.68) ALDH1A1SMN1; SMN2HPGDNPC1RAB9A
SCHEMBL7885963 0.71 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2HPGDNPC1RAB9A
SCHEMBL27961616 0.70 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2HPGDNPC1RAB9A
SCHEMBL7127961 0.70 SMN1; SMN2 (0.59) ALDH1A1SMN1; SMN2HPGDNPC1RAB9A
SCHEMBL20960732 0.68 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2HPGDNPC1RAB9A
SCHEMBL4430978 0.68 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2HPGDNPC1RAB9A
SCHEMBL29268398 0.67 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2HPGDNPC1RAB9A
SCHEMBL5282738 0.67 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2HPGDNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110204465-B Method for synthesizing homoallylamine compound by photocatalysis 西北师范大学 2021-05-11 CN disclosed