Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | LATS1 | O95835 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23458507 | 0.77 | RAB9A (0.68) | MAPTPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL29606391 | 0.77 | L3MBTL1 (0.45) | MAPTPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL28575556 | 0.75 | PIK3CD (0.43) | MAPTPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL28560936 | 0.75 | LATS1 (0.43) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL28561310 | 0.74 | NPC1 (0.54) | MAPTNPC1RAB9AKDM4EMYC | |
| SCHEMBL26833283 | 0.74 | RAB9A (0.64) | MAPTNPC1RAB9AKDM4E | |
| SCHEMBL29606206 | 0.74 | RAB9A (0.64) | MAPTNPC1RAB9AKDM4E | |
| SCHEMBL28570235 | 0.73 | CYP2A6 (0.48) | MAPTNPC1RAB9AKDM4EMYC | |
| SCHEMBL20519963 | 0.73 | RAB9A (0.76) | PIK3CDPIK3CAPI4KAPI4KBNPC1 | |
| SCHEMBL17984875 | 0.72 | APP (0.53) | NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108373476-B | Kinase inhibitor and preparation and application thereof | 成都地奥制药集团有限公司 | 2021-06-01 | — | — | CN | disclosed |