Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 12/20 | 0.52 |
| ▸ | MET | P08581 | 5/20 | 0.42 |
| ▸ | RPS6KA4 | O75676 | 2/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22930553 | 0.81 | RPS6KA5 (0.49) | RPS6KA5METRPS6KA4CDC7CDK2 | |
| SCHEMBL4546571 | 0.81 | RPS6KA5 (0.52) | RPS6KA5METRPS6KA4CDC7CDK2 | |
| SCHEMBL2593923 | 0.77 | P2RX7 (0.50) | RPS6KA5METRPS6KA4CDC7CDK2 | |
| SCHEMBL28761669 | 0.74 | RPS6KA5 (0.41) | RPS6KA5METRPS6KA4CDC7CDK2 | |
| SCHEMBL17889739 | 0.74 | RPS6KA5 (0.45) | RPS6KA5METRPS6KA4CDC7CDK2 | |
| SCHEMBL477271 | 0.72 | MEN1 (0.58) | — | |
| SCHEMBL13378058 | 0.71 | RPS6KA5 (0.59) | RPS6KA5METRPS6KA4CDC7CDK2 | |
| SCHEMBL1446137 | 0.69 | RPS6KA5 (0.57) | RPS6KA5METRPS6KA4CDC7CDK2 | |
| SCHEMBL1472997 | 0.69 | RPS6KA5 (0.57) | RPS6KA5METRPS6KA4CDC7CDK2 | |
| SCHEMBL256322 | 0.69 | RPS6KA5 (0.57) | RPS6KA5METRPS6KA4CDC7CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279849-A | N-difluoromethyl azaindole compound and synthesis method thereof | 丽水学院 | 2021-01-29 | — | — | CN | disclosed |